Faculty

Steven Pipe, MD Professor of Pediatrics and Pathology Laurence A. Boxer Research Professor of Pediatrics and Communicable Diseases Pediactric Medical Director Hemophilia and Coagulation Disorders Program Director Special Coagulation Laboratory University of Michigan Ann Arbor, MI

Lauren E. Siewny, MD Assistant Professor of Surgery Department of Surgery, Division of Emergency Medicine Duke University Medical Center Durham, NC

Statement of Need

Patients with hemophilia and other benign rare blood disorders frequently present to the emergency department with a wide variety of bleeding-related issues. Hence, it is important that clinicians in the emergency setting be aware of optimal approaches to treat and monitor patients with these diseases and to accurately recognize these conditions in patients who may not have yet been diagnosed.

This CME Outfitters LLC Snack features case-based learning designed to facilitate problem-solving and therefore bridge the gap between evidence and actionable changes in practice as they pertain to updated guidelines, new treatments, and emerging therapies that will help physicians and other professionals who work in the ED with identifying, monitoring, and managing patients with hemophilia.

Learning Objectives

At the end of this CE activity, participants should be able to:

• Recognize and manage complications associated with benign rare blood disorders such as hemophilia in the emergency department setting.
• Evaluate clinical data for the efficacy and safety of current and emerging treatments for benign rare blood disorders.
• Implement personalized, evidence-based approaches to managing benign rare blood disorders in the emergency department setting.

The following learning objectives pertain only to those requesting CNE or CPE credit:

• Explain the complications associated with benign rare blood disorders such as hemophilia in the emergency department setting.
• Describe the clinical data for the efficacy and safety of current and emerging treatments for benign rare blood disorders.
• Identify personalized, evidence-based approaches for managing benign rare blood disorders in the emergency department setting.

Financial Support

Supported by educational grants from CSL Behring LLC and Shire, now part of Takeda.

Target Audience

Emergency department physicians, physician assistants, nurse practitioners, nurses, and pharmacists.

Credit Information

CME Credit (Physicians):
CME Outfitters, LLC, is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

CME Outfitters, LLC, designates this enduring material for a maximum of 0.5 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

CPE Credit (Pharmacists):
CME Outfitters, LLC, is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. 0.5 contact hours (0.05 CEUs) Universal Activity Number:
Enduring: 0376-0000-19-025-H01-P

Type: Knowledge-based

ABIM MOC Credit:
MOC Points available for Internal Medicine and General Medicine Board Certified Physicians.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.5 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

Learning Format:
Enduring Material

MIPS Improvement Activity: This activity counts towards MIPS Improvement Activity requirements under the Medicare Access and CHIP Reauthorization Act of 2015 (MACRA). Clinicians should submit their improvement activities by attestation via the CMS Quality Payment Program website.

Note to Physician Assistants: AAPA accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credit^TM from organizations accredited by the Accreditation Council for Continuing Medical Education.

Note to Nurse Practitioners: Nurse Practitioners can apply for AMA PRA Category 1 Credit™through the American Academy of Nurse Practitioners (AANP). AANP will accept AMA PRA Category 1 Credit™ from organizations accredited by the Accreditation Council for Continuing Medical Education. Nurse practitioners can also apply for credit through their state boards.

Post-tests, credit request forms, and activity evaluations must be completed online (requires free account activation), and participants can print their certificate or statement of credit immediately (75% pass rate required). This website supports all browsers except Internet Explorer for Mac. For complete technical requirements and privacy policy, visit https://www.cmeoutfitters.com/privacy-and-confidentiality-policy/.

Disclosure Declaration

It is the policy of CME Outfitters, LLC, to ensure independence, balance, objectivity, and scientific rigor and integrity in all of their CE activities. Faculty must disclose to the participants any relationships with commercial companies whose products or devices may be mentioned in faculty presentations, or with the commercial supporter of this CE activity. CME Outfitters, LLC, has evaluated, identified, and attempted to resolve any potential conflicts of interest through a rigorous content validation procedure, use of evidence-based data/research, and a multidisciplinary peer review process. The following information is for participant information only. It is not assumed that these relationships will have a negative impact on the presentations.

Dr. Pipe reports that he receives research support from Siemans and consulting fees from Apcintex; Bayer Corporation; BioMarin; Bioverativ Inc.; Catalyst Biosciences; CSL Behring; HEMA Biologics, LLC; Freeline; Novo Nordisk; Pfizer Inc.; F. Hoffmann-La Roche Ltd/Genentech, Inc.; sanofi-aventis U.S. LLC; Shire; Spark Therapeutics, Inc., and uniQure.

Dr. Siewny has no disclosures to report.

Jeffrey Helfand, DO (peer reviewer) has no disclosures to report.

Mae Ochoa, RPh (peer reviewer) has no disclosures to report.

Kavitha Ramanchandran, PhD (planning committee) has no disclosures to report.

Jan Perez (planning committee) has no disclosures to report.

Sharon Tordoff (planning committee) has no disclosures to report.

Disclosures were obtained from the CME Outfitters, LLC staff: No disclosures to report.

CME Outfitters, LLC and the faculty do not endorse the use of any product outside of the FDA labeled indications. Medical professionals should not utilize the procedures, products, or diagnosis techniques discussed during this activity without evaluation of their patient for contraindications or dangers of use.

Questions about this activity? Call us at 877.CME.PROS(877.263.7767).

SN-109-071219-90